Searchable abstracts of presentations at key conferences in endocrinology

ea0086p206 | Metabolism, Obesity and Diabetes | SFEBES2022

Circulating levels of adipose-derived lipokines correlate positively with fasting insulin in states of increased insulin insensitivity in humans

Gamwell Jonathan , Riecan Martin , Pinnick Katherine , Kuda Ondrej , Hodson Leanne

Introduction: Palmitoleate, a proposed adipose tissue (AT)-derived lipokine, has been suggested to contribute to glucose homeostasis. However, data relating to the association between circulating palmitoleate and markers of insulin sensitivity in humans are equivocal. Recently, AT-derived fatty acid-hydroxy fatty acids (FAHFAs) have also been suggested to play a role in glucose homeostasis by increasing glucose uptake in AT. Again, data is conflicting for the association betwe...